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On the other hand, the exact same focus of Acquire but not other CB1R agonists, raises intracellular Ca2+ concentration via Gq/eleven protein in transfected HEK-293 cells and cultured hippocampal neurons with endogenous receptor expression [ninety three]. Moreover, in mice hippocampal slices, CB1R expressed in astrocytes is coupled to Gq/11, raises
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